Phenotypes associated with this allele

• Allele Symbol: Pdyn⁺
• Allele Name: wild type
• Allele ID: MGI:2431671
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Pdyn^tm1(cre)Czer/Pdyn^+	B6.Cg-Pdyn^tm1(cre)Czer	MGI:3715624
cn2	Mc4r^tm1Lowl/Mc4r^tm1Lowl Pdyn^tm1.1(cre)Mjkr/Pdyn^+	involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6	MGI:5609692

Genotype
MGI:3715624

ht1

• Allelic Composition: Pdyn^tm1(cre)Czer/Pdyn⁺
• Genetic Background: B6.Cg-Pdyn^tm1(cre)Czer

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

increased susceptibility to pharmacologically induced seizures ( J:122651 )

• mice have a intermittent seizure threshold at 36.7+/-1.93mg PTZ/kg compared to 39.1+/-0.96mg PTZ/kg in wild-type and 32.7+/-1.17mg PTZ/kg in homozygous mice

behavior/neurological

increased susceptibility to pharmacologically induced seizures ( J:122651 )

• mice have a intermittent seizure threshold at 36.7+/-1.93mg PTZ/kg compared to 39.1+/-0.96mg PTZ/kg in wild-type and 32.7+/-1.17mg PTZ/kg in homozygous mice

Genotype
MGI:5609692

cn2

• Allelic Composition: Mc4r^tm1Lowl/Mc4r^tm1Lowl; Pdyn^{tm1.1(cre)Mjkr}/Pdyn⁺
• Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6

growth/size/body

obese ( J:216397 )