Phenotypes associated with this allele

• Allele Symbol: Fyn⁺
• Allele Name: wild type
• Allele ID: MGI:2430704
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Fyn^tm1Yik/Fyn^+	involves: C57BL/6 * CBA	MGI:3693457
cx2	Fyn^tm1Sor/Fyn^+ Tg(Camk2a-Fyn-531)1Nko/0	involves: 129S7/SvEvBrd * C57BL/6 * CBA	MGI:2652121

Genotype
MGI:3693457

ht1

• Allelic Composition: Fyn^tm1Yik/Fyn⁺
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

prolonged circadian behavior period ( J:63170 )

• under constant dark condition, exhibit longer circadian periods in wheel-running activity than wild-type

Genotype
MGI:2652121

cx2

• Allelic Composition: Fyn^tm1Sor/Fyn⁺; Tg(Camk2a-Fyn-531)1Nko/0
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA

mortality/aging

premature death ( J:59490 )

• sudden death after weaning; survival rate shows correlation with level of transgene expression

behavior/neurological

abnormal motor capabilities/coordination/movement ( J:59490 )

• lines expressing high levels of the transgene show spontaneous running and bouncing fits

tonic seizures ( J:59490 )

• tonic convulsion

nervous system

tonic seizures ( J:59490 )

• tonic convulsion