All Phenotypes Gls<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gls⁺
wild type
MGI:2430632

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Gls^tm2.1Sray/Gls⁺ Tg(CAG-cre/Esr1*)5Amc/0	involves: 129S1/Sv * C57BL/6 * CBA	MGI:5784520

Allelic Composition	Gls^tm2.1Sray/Gls⁺ Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background	involves: 129S1/Sv * C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gls^tm2.1Sray mutation (1 available); any Gls mutation (42 available)
Tg(CAG-cre/Esr1*)5Amc mutation (9 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

impaired behavioral response to amphetamine ( J:230564 )

• attenuated locomotor response to amphetamine in tamoxifen-treated mice as compared to controls

• amphetamine-induced hyperlocomotion is blocked in open field test

abnormal locomotor activation ( J:230564 )

• decrease in fine movements, but not rearing, following administration of amphetamine in tamoxifen-treated mice as compared to controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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