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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gapdh+
wild type
MGI:2430564
Summary 14 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Gapdhm1Neu/Gapdh+ C3.Cg-Gapdhm1Neu MGI:3808729
ht2
 		Gapdhm2Neu/Gapdh+ C3.Cg-Gapdhm2Neu MGI:3808731
ht3
 		Gapdhm3Neu/Gapdh+ C3.Cg-Gapdhm3Neu MGI:3808733
ht4
 		Gapdhm4Neu/Gapdh+ C3.Cg-Gapdhm4Neu MGI:3808734
ht5
 		GapdhM5Neu/Gapdh+ C3.Cg-GapdhM5Neu MGI:3808736
ht6
 		GapdhM6Neu/Gapdh+ C3.Cg-GapdhM6Neu MGI:3808739
ht7
 		GapdhM7Neu/Gapdh+ C3.Cg-GapdhM7Neu MGI:3808740
ht8
 		GapdhM8Neu/Gapdh+ C3.Cg-GapdhM8Neu MGI:3808743
ht9
 		GapdhM9Neu/Gapdh+ C3.Cg-GapdhM9Neu MGI:3808744
ht10
 		Gapdhem1(IMPC)Mbp/Gapdh+ C57BL/6N-Gapdhem1(IMPC)Mbp/MbpMmucd MGI:7388739
ht11
 		Gapdhm4Neu/Gapdh+ involves: 101/El * C3H/El MGI:3663930
ht12
 		Gapdhm3Neu/Gapdh+ involves: 101/El * C3H/El MGI:3663928
ht13
 		Gapdhm2Neu/Gapdh+ involves: 101/El * C3H/El MGI:3663926
ht14
 		Gapdhm1Neu/Gapdh+ involves: 101/El * C3H/El MGI:3663924


Genotype
MGI:3808729
ht1
Allelic
Composition		 Gapdhm1Neu/Gapdh+
Genetic
Background		 C3.Cg-Gapdhm1Neu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gapdhm1Neu mutation (1 available); any Gapdh mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity ( J:126359 )
• Gapdh activity is approximately 50-55% of wild-type levels




Genotype
MGI:3808731
ht2
Allelic
Composition		 Gapdhm2Neu/Gapdh+
Genetic
Background		 C3.Cg-Gapdhm2Neu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gapdhm2Neu mutation (1 available); any Gapdh mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity ( J:126359 )
• Gapdh activity is approximately 50-55% of wild-type levels




Genotype
MGI:3808733
ht3
Allelic
Composition		 Gapdhm3Neu/Gapdh+
Genetic
Background		 C3.Cg-Gapdhm3Neu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gapdhm3Neu mutation (1 available); any Gapdh mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity ( J:126359 )
• Gapdh activity is approximately 50-55% of wild-type levels




Genotype
MGI:3808734
ht4
Allelic
Composition		 Gapdhm4Neu/Gapdh+
Genetic
Background		 C3.Cg-Gapdhm4Neu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gapdhm4Neu mutation (1 available); any Gapdh mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, incomplete penetrance ( J:126359 )
• number of heterzygous offspring is reduced

homeostasis/metabolism
decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity ( J:126359 )
• Gapdh activity is approximately 50-55% of wild-type levels




Genotype
MGI:3808736
ht5
Allelic
Composition		 GapdhM5Neu/Gapdh+
Genetic
Background		 C3.Cg-GapdhM5Neu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
GapdhM5Neu mutation (1 available); any Gapdh mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity ( J:126359 )
• Gapdh activity is approximately 50-55% of wild-type levels




Genotype
MGI:3808739
ht6
Allelic
Composition		 GapdhM6Neu/Gapdh+
Genetic
Background		 C3.Cg-GapdhM6Neu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
GapdhM6Neu mutation (1 available); any Gapdh mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, incomplete penetrance ( J:126359 )
• number of heterzygous offspring is reduced

homeostasis/metabolism
decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity ( J:126359 )
• Gapdh activity is approximately 50-55% of wild-type levels




Genotype
MGI:3808740
ht7
Allelic
Composition		 GapdhM7Neu/Gapdh+
Genetic
Background		 C3.Cg-GapdhM7Neu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
GapdhM7Neu mutation (1 available); any Gapdh mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity ( J:126359 )
• Gapdh activity is approximately 50-55% of wild-type levels




Genotype
MGI:3808743
ht8
Allelic
Composition		 GapdhM8Neu/Gapdh+
Genetic
Background		 C3.Cg-GapdhM8Neu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
GapdhM8Neu mutation (1 available); any Gapdh mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity ( J:126359 )
• Gapdh activity is approximately 50-55% of wild-type levels




Genotype
MGI:3808744
ht9
Allelic
Composition		 GapdhM9Neu/Gapdh+
Genetic
Background		 C3.Cg-GapdhM9Neu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
GapdhM9Neu mutation (1 available); any Gapdh mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity ( J:126359 )
• Gapdh activity is approximately 50-55% of wild-type levels




Genotype
MGI:7388739
ht10
Allelic
Composition		 Gapdhem1(IMPC)Mbp/Gapdh+
Genetic
Background		 C57BL/6N-Gapdhem1(IMPC)Mbp/MbpMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gapdhem1(IMPC)Mbp mutation (1 available); any Gapdh mutation (39 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system

embryo

growth/size/body
embryonic growth retardation ( J:211773 )
IMPC - UCD

vision/eye
cataract ( J:211773 )
IMPC - UCD




Genotype
MGI:3663930
ht11
Allelic
Composition		 Gapdhm4Neu/Gapdh+
Genetic
Background		 involves: 101/El * C3H/El
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gapdhm4Neu mutation (1 available); any Gapdh mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating enzyme/coenzyme activity ( J:15476 )
• 50% erythrocyte enzyme activity




Genotype
MGI:3663928
ht12
Allelic
Composition		 Gapdhm3Neu/Gapdh+
Genetic
Background		 involves: 101/El * C3H/El
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gapdhm3Neu mutation (1 available); any Gapdh mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating enzyme/coenzyme activity ( J:15477 )
• 50% erythrocyte enzyme activity




Genotype
MGI:3663926
ht13
Allelic
Composition		 Gapdhm2Neu/Gapdh+
Genetic
Background		 involves: 101/El * C3H/El
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gapdhm2Neu mutation (1 available); any Gapdh mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating enzyme/coenzyme activity ( J:15476 )
• 50% erythrocyte enzyme activity




Genotype
MGI:3663924
ht14
Allelic
Composition		 Gapdhm1Neu/Gapdh+
Genetic
Background		 involves: 101/El * C3H/El
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gapdhm1Neu mutation (1 available); any Gapdh mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating enzyme/coenzyme activity ( J:15477 )
• the original mutant showed a 75% erythrocyte enzyme activity but subsequent generations show 50% activity




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory