Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dab1tm3.1Cpr mutation
(0 available);
any
Dab1 mutation
(77 available)
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nervous system
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N |
• brain histology is normal
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dab1tm1Cpr mutation
(1 available);
any
Dab1 mutation
(77 available)
Dab1tm3.1Cpr mutation
(0 available);
any
Dab1 mutation
(77 available)
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nervous system
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N |
• mice exhibit a normal cerebellum and preplate splitting
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• late born neurons migrate into the marginal zone unlike in wild-type mice
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• the neocortical marginal zone is thinner than in wild-type mice and crowded with small cells
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• mice exhibit a splitting of the stratum pyramidale in the CA1 region
• the ectopic pyramidal layer is closer to the hippocampal fissure, further from the alveus and becomes the main layer in the CA2 region
• however, the CA3 region and dentate gyrus develop normally
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cellular
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• late born neurons migrate into the marginal zone unlike in wild-type mice
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dab1tm3.1Cpr mutation
(0 available);
any
Dab1 mutation
(77 available)
Relnrl mutation
(3 available);
any
Reln mutation
(209 available)
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nervous system
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N |
• the hippocampus and neocortex are normal
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Analysis Tools