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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lpar2tm1Jch
targeted mutation 1, Jerold Chun
MGI:2387979
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lpar2tm1Jch/Lpar2tm1Jch involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:2684650
cx2
 		Plppr4tm1Roni/Plppr4tm1Roni
Lpar2tm1Jch/Lpar2tm1Jch 		involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:4431244


Genotype
MGI:2684650
hm1
Allelic
Composition		 Lpar2tm1Jch/Lpar2tm1Jch
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lpar2tm1Jch mutation (0 available); any Lpar2 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:78925 )
• homozygous animals were grossly indistinguishable from littermates in appearance, size, longevity, reproduction and behavior




Genotype
MGI:4431244
cx2
Allelic
Composition		 Plppr4tm1Roni/Plppr4tm1Roni
Lpar2tm1Jch/Lpar2tm1Jch
Genetic
Background		 involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lpar2tm1Jch mutation (0 available); any Lpar2 mutation (13 available)
Plppr4tm1Roni mutation (0 available); any Plppr4 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:157318 )
N
• mice do not exhibit increased mortality around P21

nervous system
nervous system phenotype ( J:157318 )
N
• mice do not exhibit seizure activity or epileptic discharge
abnormal miniature excitatory postsynaptic currents ( J:157318 )
• CA1 pyramidal cells exhibit a reduced miniature excitatory postsynaptic current frequency compared to in wild-type mice

behavior/neurological
behavior/neurological phenotype ( J:157318 )
N
• mice do not exhibit seizure activity or epileptic discharge

growth/size/body
growth/size/body region phenotype ( J:157318 )
N
• mice exhibit normal body weight




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory