Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igh-7tm1Led mutation
(1 available);
any
Igh-7 mutation
(1 available)
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immune system
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• there is almost a two-fold reduction in the number of eosinophils recruited to sites of T. spiralis infection in tongue skeletal muscle
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hematopoietic system
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• there is almost a two-fold reduction in the number of eosinophils recruited to sites of T. spiralis infection in tongue skeletal muscle
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|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igh-7tm1Led mutation
(1 available);
any
Igh-7 mutation
(1 available)
|
|
|
immune system
N |
• in spite of the absence of IgE, mice display typical systemic anaphylactic responses
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hematopoietic system
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• in the bone marrow, blood and spleen
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immune system
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• in the bone marrow, blood and spleen
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• increased circulating immune complexes reactive to complement component 1 q
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• yet decreased compared to Lyn single mutant
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• yet decreased compared to Lyn single mutant
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homeostasis/metabolism