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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Kcna4tm1Lndn
targeted mutation 1, Barry London
MGI:2386331
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Kcna4tm1Lndn/Kcna4tm1Lndn involves: 129S4/SvJae * C57BL/6 MGI:3041867


Genotype
MGI:3041867
hm1
Allelic
Composition		 Kcna4tm1Lndn/Kcna4tm1Lndn
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcna4tm1Lndn mutation (0 available); any Kcna4 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
seizures ( J:48415 )
• homozygous null mice were viable, fertile and grossly normal; however, <10% of mutants displayed spontaneous seizure activity

nervous system
seizures ( J:48415 )
• homozygous null mice were viable, fertile and grossly normal; however, <10% of mutants displayed spontaneous seizure activity




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory