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Allele Symbol Allele Name Allele ID |
Scnn1atm1.1Hum targeted mutation 1.1, Edith Hummler MGI:2384527 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• when mice are fed a normal sodium diet, cortical collecting ducts exhibit no significant sodium, chloride, or potassium ion transport unlike wild-type ducts from similarly treated wild-type mice
• when mice are fed a sodium-depleted diet, cortical collecting ducts absorb sodium without forming a lumen-negative transepithelial voltage unlike ducts from similarly treated wild-type mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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