Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctbp1tm1Sor mutation
(1 available);
any
Ctbp1 mutation
(35 available)
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mortality/aging
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• about 23% of homozygotes die before 20 days of age
• survivors are fertile
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growth/size/body
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• 30% smaller than wild-type controls
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mortality/aging
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• about 26% of homozygotes die before 20 days of age
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growth/size/body
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• smaller than wild-type controls
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mortality/aging
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• die between E15.5 and E18.5
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growth/size/body
cardiovascular system
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• extensive hemorrhage in embryos
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skeleton
muscle
embryo
nervous system
embryo
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• development arrested at the turning stage
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embryo
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• arrested at the headfold stage
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• blebs or blisters form on the neuroectoderm
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cardiovascular system
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• little heart morphogenesis
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nervous system
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• blebs or blisters form on the neuroectoderm
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