All Phenotypes Ucp3<tm1Brnd> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ucp3^tm1Brnd
targeted mutation 1, Martin D Brand
MGI:2183204

Summary

2 genotypes

Allelic Composition	Ucp3^tm1Brnd/Ucp3^tm1Brnd
Genetic Background	B6.Cg-Ucp3^tm1Brnd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ucp3^tm1Brnd mutation (0 available); any Ucp3 mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal mitochondrial physiology ( J:73905 )

• skeletal muscle mitochondria proton conductance is insensitive to superoxide treatment unlike wild-type mitochondria

Allelic Composition	Ucp3^tm1Brnd/Ucp3^tm1Brnd
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ucp3^tm1Brnd mutation (0 available); any Ucp3 mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

• when fed a high-fat diet, intramuscular triglyceride levels are lower than in similarly treated wild-type mice

muscle

• when fed a high-fat diet, intramuscular triglyceride levels are lower than in similarly treated wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23