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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ppef1tm1Nat
targeted mutation 1, Jeremy Nathans
MGI:2182810
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ppef1tm1Nat/Ppef1tm1Nat involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3040618
cx2
 		Ppef1tm1Nat/Ppef1tm1Nat
Ppef2tm1Nat/Ppef2tm1Nat 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3040621
cx3
 		Ppef1tm1Nat/Y
Ppef2tm1Nat/Ppef2tm1Nat 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3040622
ot4
 		Ppef1tm1Nat/Y involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3040619


Genotype
MGI:3040618
hm1
Allelic
Composition		 Ppef1tm1Nat/Ppef1tm1Nat
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppef1tm1Nat mutation (0 available); any Ppef1 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:72941 )
• authors state mice are viable, fertile, with no overt abnormalities




Genotype
MGI:3040621
cx2
Allelic
Composition		 Ppef1tm1Nat/Ppef1tm1Nat
Ppef2tm1Nat/Ppef2tm1Nat
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppef1tm1Nat mutation (0 available); any Ppef1 mutation (3 available)
Ppef2tm1Nat mutation (0 available); any Ppef2 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
vision/eye phenotype ( J:72941 )
N
• normal rod function
• normal retinal histology at 3 months
• no retinal degeneration for 3 months, no later time points measured

normal phenotype
no abnormal phenotype detected ( J:72941 )
• authors state mice are viable, fertile, with no overt abnormalities




Genotype
MGI:3040622
cx3
Allelic
Composition		 Ppef1tm1Nat/Y
Ppef2tm1Nat/Ppef2tm1Nat
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppef1tm1Nat mutation (0 available); any Ppef1 mutation (3 available)
Ppef2tm1Nat mutation (0 available); any Ppef2 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
vision/eye phenotype ( J:72941 )
N
• normal rod function
• normal retinal histology at 3 months of age
• no retinal degeneration for 3 months, no later time points measured

normal phenotype
no abnormal phenotype detected ( J:72941 )
• authors state mice are viable, fertile, with no overt abnormalities




Genotype
MGI:3040619
ot4
Allelic
Composition		 Ppef1tm1Nat/Y
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppef1tm1Nat mutation (0 available); any Ppef1 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:72941 )
• authors state mice are viable, fertile, with no overt abnormalities




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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory