All Phenotypes H1f0<tm1Ais> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

H1f0^tm1Ais
targeted mutation 1, Art I Skoultchi
MGI:2182779

Summary

6 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	H1f0^tm1Ais/H1f0^tm1Ais	involves: 129P2/OlaHsd * C57BL/6	MGI:3844493
cx2	H1f0^tm1Ais/H1f0^tm1Ais H1f2^tm2Ais/H1f2^tm2Ais H1f3^tm2Ais/H1f3^tm2Ais H1f4^tm2Ais/H1f4^tm2Ais	involves: 129/Sv * C57BL/6 * SJL	MGI:2674074
cx3	H1f0^tm1Ais/H1f0^tm1Ais H1f2^tm2Ais/H1f2^tm2Ais H1f4^tm2Ais/H1f4^tm2Ais	involves: 129/Sv * C57BL/6 * SJL	MGI:2674076
cx4	H1f0^tm1Ais/H1f0^tm1Ais H1f2^tm1Ais/H1f2^tm1Ais	involves: 129P2/OlaHsd * C57BL	MGI:3844478
cx5	H1f0^tm1Ais/H1f0^tm1Ais H1f4^tm1Ais/H1f4^tm1Ais	involves: 129P2/OlaHsd * C57BL/6	MGI:3844467
cx6	H1f0^tm1Ais/H1f0^tm1Ais H1f3^tm1Ais/H1f3^tm1Ais	involves: 129P2/OlaHsd * C57BL/6	MGI:3844473

Allelic Composition	H1f0^tm1Ais/H1f0^tm1Ais
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H1f0^tm1Ais mutation (0 available); any H1f0 mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:26848 )

• viable, fertile and overtly normal

• no apparent anatomic or histologic abnormalities

• no defects in cell division patterns

Allelic Composition	H1f0^tm1Ais/H1f0^tm1Ais H1f2^tm2Ais/H1f2^tm2Ais H1f3^tm2Ais/H1f3^tm2Ais H1f4^tm2Ais/H1f4^tm2Ais
Genetic Background	involves: 129/Sv * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H1f0^tm1Ais mutation (0 available); any H1f0 mutation (14 available)
H1f2^tm2Ais mutation (0 available); any H1f2 mutation (17 available)
H1f3^tm2Ais mutation (0 available); any H1f3 mutation (8 available)
H1f4^tm2Ais mutation (0 available); any H1f4 mutation (10 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:83954 )

• no homozygotes are born

embryo

abnormal embryonic tissue morphology ( J:83954 )

• E9.5 embryos are severely retarded and abnormal

Allelic Composition	H1f0^tm1Ais/H1f0^tm1Ais H1f2^tm2Ais/H1f2^tm2Ais H1f4^tm2Ais/H1f4^tm2Ais
Genetic Background	involves: 129/Sv * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H1f0^tm1Ais mutation (0 available); any H1f0 mutation (14 available)
H1f2^tm2Ais mutation (0 available); any H1f2 mutation (17 available)
H1f4^tm2Ais mutation (0 available); any H1f4 mutation (10 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:83954 )

• homozygotes are under represented in litters at birth

growth/size/body

decreased body size ( J:83954 )

• mice are much smaller at birth and as adults

immune system

small thymus ( J:83954 )

• histologically normal however

reproductive system

reduced fertility ( J:83954 )

• both male and female mutants are fertile when crossed to wild-type mice but display reduced fertility when crossed to one another

hematopoietic system

small thymus ( J:83954 )

• histologically normal however

endocrine/exocrine glands

small thymus ( J:83954 )

• histologically normal however

Allelic Composition	H1f0^tm1Ais/H1f0^tm1Ais H1f2^tm1Ais/H1f2^tm1Ais
Genetic Background	involves: 129P2/OlaHsd * C57BL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H1f0^tm1Ais mutation (0 available); any H1f0 mutation (14 available)
H1f2^tm1Ais mutation (0 available); any H1f2 mutation (17 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:72858 )

Allelic Composition	H1f0^tm1Ais/H1f0^tm1Ais H1f4^tm1Ais/H1f4^tm1Ais
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H1f0^tm1Ais mutation (0 available); any H1f0 mutation (14 available)
H1f4^tm1Ais mutation (0 available); any H1f4 mutation (10 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:72858 )

Allelic Composition	H1f0^tm1Ais/H1f0^tm1Ais H1f3^tm1Ais/H1f3^tm1Ais
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H1f0^tm1Ais mutation (0 available); any H1f0 mutation (14 available)
H1f3^tm1Ais mutation (0 available); any H1f3 mutation (8 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:72858 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24