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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rfngtm1Grid
targeted mutation 1, Tom Gridley
MGI:2182609
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rfngtm1Grid/Rfngtm1Grid involves: 129S1/Sv * C57BL/6J MGI:3039552
cx2
 		Lfngtm1Grid/Lfngtm1Grid
Rfngtm1Grid/Rfngtm1Grid 		involves: 129S1/SvImJ * C57BL/6J MGI:3039551


Genotype
MGI:3039552
hm1
Allelic
Composition		 Rfngtm1Grid/Rfngtm1Grid
Genetic
Background		 involves: 129S1/Sv * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rfngtm1Grid mutation (0 available); any Rfng mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:77247 )
• no phenotypic abnormalities were detected
• no function detected for this gene




Genotype
MGI:3039551
cx2
Allelic
Composition		 Lfngtm1Grid/Lfngtm1Grid
Rfngtm1Grid/Rfngtm1Grid
Genetic
Background		 involves: 129S1/SvImJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lfngtm1Grid mutation (1 available); any Lfng mutation (34 available)
Rfngtm1Grid mutation (0 available); any Rfng mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
skeleton phenotype ( J:77247 )
N
• phenotypes of double homozygotes were identical to those of mice homozygous for Lfngtm1Grid only
abnormal costovertebral joint morphology ( J:48810 )
• some ribs are detached from the vertebral column
abnormal vertebrae morphology ( J:48810 )
• regular metameric pattern of vertebrae is disrupted




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory