Lfng^tm1Grid
Targeted Allele Detail

Summary

• Symbol: Lfng^tm1Grid
• Name: LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; targeted mutation 1, Tom Gridley
• MGI ID: MGI:1933734
• Synonyms: Lfng^-, Lfng^LacZ
• Gene: Lfng Location: Chr5:140593096-140601300 bp, + strand Genetic Position: Chr5, 79.15 cM
• Alliance: Lfng^tm1Grid page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:48810
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• A lacZ-neomycin resistance cassette replaced 0.7kb of the gene including most of exon 1. (J:48810)

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lfng Mutation: 32 strains or lines available

References

• Original: J:48810 Zhang N, et al., Defects in somite formation in lunatic fringe-deficient mice. Nature. 1998 Jul 23;394(6691):374-7
• All: 17 reference(s)