All Phenotypes Cntf<tm1Gdy> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cntf^tm1Gdy
targeted mutation 1, George D Yancopoulos
MGI:2181048

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cntf^tm1Gdy/Cntf^tm1Gdy	involves: 129P2/OlaHsd * C57BL/6	MGI:3618320

Allelic Composition	Cntf^tm1Gdy/Cntf^tm1Gdy
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cntf^tm1Gdy mutation (0 available); any Cntf mutation (13 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:29357 )

N	• homozygous mice do not exhibit motor neuron deficits at birth, however later stages were not analyzed

abnormal motor neuron morphology ( J:66057 )

• motorneuron sprouting is not observed as in wild-type following partial muscle denervation or botulinum toxin induced paralysis at 2 and 8 months of age

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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