Analysis Tools|
Allele Symbol Allele Name Allele ID |
Bax+ wild type MGI:2176703 |
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| Summary |
5 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• cultures of sympathetic neurons grown in the presence of NGF before being deprived of NGF, die with slower kinetics than wild-type, such that after 8 days, 14% of neurons remain viable compared to none in controls
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• modest 13% increase in the total number of facial motor neurons at 4 weeks of age relative to wild-type
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• male germ cells begin to disappear after birth and are gone by 4 weeks of age
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• male germ cells begin to disappear after birth and are gone by 4 weeks of age
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• decreased number of ovarian follicles
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• absence of spermatogonia
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• decreased number of ovarian follicles
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• absence of spermatogonia
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• a swaying ataxia is found in the third week of age, the same as in simple lurcher heterozygotes
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• gaps in the Purkinje cell layer found by 15 days of age
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• much smaller internal granule cell layer as early as 15 days of age
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• increased apoptosis of primordial germ cells
• decreased germ cell proliferation
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• increased apoptosis of primordial germ cells
• decreased germ cell proliferation
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 01/06/2026 MGI 6.24 |
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