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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Marcksl1tm1Fsh
targeted mutation 1, Gordon Fishell
MGI:2176277
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Marcksl1tm1Fsh/Marcksl1tm1Fsh involves: 129S4/SvJae MGI:3694121


Genotype
MGI:3694121
hm1
Allelic
Composition		 Marcksl1tm1Fsh/Marcksl1tm1Fsh
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Marcksl1tm1Fsh mutation (0 available); any Marcksl1 mutation (8 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal macrophage physiology ( J:115146 )
• macrophages display normal phagocytosis and localization compared to wild-type cells

hematopoietic system
abnormal macrophage physiology ( J:115146 )
• macrophages display normal phagocytosis and localization compared to wild-type cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory