Phenotypes associated with this allele

• Allele Symbol: Adip1^LG/J
• Allele Name: LG/J
• Allele ID: MGI:2153875
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Adip1^LG/J/Adip1^LG/J	involves: LG/J * SM/J	MGI:2175229
cx2	Adip1^LG/J/? Capn10^tm1Chev/Capn10^+	(B6.129-Capn10^tm1Chev x LG/J)F1	MGI:4365746

Genotype
MGI:2175229

hm1

• Allelic Composition: Adip1^LG/J/Adip1^LG/J
• Genetic Background: involves: LG/J * SM/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased white adipose tissue amount ( J:62610 )

• increased adiposity in male animals

Genotype
MGI:4365746

cx2

• Allelic Composition: Adip1^LG/J/?; Capn10^tm1Chev/Capn10⁺
• Genetic Background: (B6.129-Capn10^tm1Chev x LG/J)F1

homeostasis/metabolism

decreased circulating glucose level ( J:153477 )

• compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

increased circulating leptin level ( J:153477 )

• 50% increased compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

decreased circulating cholesterol level ( J:153477 )

• compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

decreased circulating free fatty acids level ( J:153477 )

• compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

decreased circulating triglyceride level ( J:153477 )

• compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

adipose tissue

increased gonadal fat pad weight ( J:153477 )

• 41% compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

increased inguinal fat pad weight ( J:153477 )

• 19% compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

increased mesenteric fat pad weight ( J:153477 )

• 41% compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

increased renal fat pad weight ( J:153477 )

• 58% compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

increased total fat pad weight ( J:153477 )

• when fed a high-fat diet, total fat pad weight is increased 37% compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice

• reproductive, renal, mesenteric, and inguinal fat pads are increased 41%, 58%, 41%, and 19% , respectively, compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 mice when fed a high-fat diet

growth/size/body

increased heart weight ( J:153477 )

• 16% compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

increased body weight ( J:153477 )

• 18% compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

increased kidney weight ( J:153477 )

• 7% compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

increased liver weight ( J:153477 )

• 34% compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

increased spleen weight ( J:153477 )

• 13% compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

cardiovascular system

increased heart weight ( J:153477 )

• 16% compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

hematopoietic system

increased spleen weight ( J:153477 )

• 13% compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

renal/urinary system

increased kidney weight ( J:153477 )

• 7% compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

liver/biliary system

increased liver weight ( J:153477 )

• 34% compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet

immune system

increased spleen weight ( J:153477 )

• 13% compared to in (C57BL/6 x LG/J-Adip1^LG/J)F1 control mice when fed a high-fat diet