All Phenotypes Cebpb<+> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cebpb⁺
wild type
MGI:2152766

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Cebpb^tm1Pfj/Cebpb⁺	B6.Cg-Cebpb^tm1Pfj	MGI:3510866
ht2	Cebpb^tm1Kish/Cebpb⁺	involves: 129P2/OlaHsd	MGI:5818724
ht3	Cebpb^tm1.1Acle/Cebpb⁺	involves: 129P2/OlaHsd * BALB/c * C57BL/6	MGI:3849866
ht4	Cebpb^tm1Vpo/Cebpb⁺	involves: 129S/SvEv * C57BL/6 * MF1	MGI:3605829

Allelic Composition	Cebpb^tm1Pfj/Cebpb⁺
Genetic Background	B6.Cg-Cebpb^tm1Pfj

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cebpb^tm1Pfj mutation (0 available); any Cebpb mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

decreased incidence of tumors by chemical induction ( J:73558 )

• heterozygous mutant mice are partially resistant to DMBA/TPA-induced papillomas

homeostasis/metabolism

decreased incidence of tumors by chemical induction ( J:73558 )

• heterozygous mutant mice are partially resistant to DMBA/TPA-induced papillomas

Allelic Composition	Cebpb^tm1Kish/Cebpb⁺
Genetic Background	involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cebpb^tm1Kish mutation (8 available); any Cebpb mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

muscle

abnormal skeletal muscle mass ( J:237461 )

• mice show a larger temporal/masseter muscle mass percentage, indicating hypotrophy of masseter muscles compared to temporal muscles and/or hypertrophy of temporal muscles compared to masseter muscles

• this temporal/masseter mass difference occurs at an early age and the difference disappears with aging

Allelic Composition	Cebpb^tm1.1Acle/Cebpb⁺
Genetic Background	involves: 129P2/OlaHsd * BALB/c * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cebpb^tm1.1Acle mutation (0 available); any Cebpb mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal skeleton morphology ( J:150006 )

• mice exhibit an intermediate phenotype between homozygotes and wild-type mice

Allelic Composition	Cebpb^tm1Vpo/Cebpb⁺
Genetic Background	involves: 129S/SvEv * C57BL/6 * MF1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cebpb^tm1Vpo mutation (1 available); any Cebpb mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

abnormal mammary gland duct morphology ( J:48513 )

• at maturity (8-12 weeks), ~20% of virgin female heterozygotes exhibit significantly enlarged, cystic ducts with bloated terminal end buds

• ductal enlargement is NOT due to accumulation of proteinaceous material in the ducts or hyperplasia of the ductal epithelium

• transplantation of heterozygous mammary epithelium into cleared mammary fat pads of nude mice results in an intermediate phenotype consisting of both normal and bloated ducts

integument

abnormal mammary gland duct morphology ( J:48513 )

• at maturity (8-12 weeks), ~20% of virgin female heterozygotes exhibit significantly enlarged, cystic ducts with bloated terminal end buds

• ductal enlargement is NOT due to accumulation of proteinaceous material in the ducts or hyperplasia of the ductal epithelium

• transplantation of heterozygous mammary epithelium into cleared mammary fat pads of nude mice results in an intermediate phenotype consisting of both normal and bloated ducts

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24