All Phenotypes Grin2d<tm1Mim> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Grin2d^tm1Mim
targeted mutation 1, Masayoshi Mishina
MGI:1928298

Summary

2 genotypes

Allelic Composition	Grin2d^tm1Mim/Grin2d^tm1Mim
Genetic Background	B6.Cg-Grin2d^tm1Mim

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grin2d^tm1Mim mutation (1 available); any Grin2d mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased startle reflex ( J:89405 )

• enhanced startle response at sound levels of 95 - 120 dB

Allelic Composition	Grin2d^tm1Mim/Grin2d^tm1Mim
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grin2d^tm1Mim mutation (1 available); any Grin2d mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:28825 )

N	• no gross histological abnormalities in the brain are seen

behavior/neurological

behavior/neurological phenotype ( J:28825 )

N	• strength, endurance and balance appeared similar to controls in a rotating rod test • exploratory behavior, anxiety and novelty preference are not affected in mutant mice as assayed by a light-dark compartment test, an elevated plus maze test and an open-field test

decreased vertical activity ( J:28825 )

• reduced number of rearings compared to controls

decreased locomotor activity ( J:28825 )

• reduced total walking activity compared to controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23