All Phenotypes Cryaa<lop18> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cryaa^lop18
lens opacity 18
MGI:1858023

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cryaa^lop18/Cryaa^lop18	involves: CBA/CaGnLeJ	MGI:2175798

Allelic Composition	Cryaa^lop18/Cryaa^lop18
Genetic Background	involves: CBA/CaGnLeJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cryaa^lop18 mutation (1 available); any Cryaa mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal lens morphology ( J:34933 )

• degeneration of lens cortex

• posterior migration of lens epithelial nuclei

lens vacuoles ( J:34933 )

• vacuoles in lens noted at E14; prominent by E16

abnormal lens fiber morphology ( J:34933 )

• abnormal fibers form at posterior pole of lens

cataract ( J:34933 )

• apparent at weaning age; progressive severity with age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract 9 multiple types		DOID:0110266	OMIM:604219	J:34933

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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