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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fgf4tm1Mrc
targeted mutation 1, Mario R Capecchi
MGI:1858005
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fgf4tm1Mrc/Fgf4tm1Mrc involves: 129S1/Sv * 129X1/SvJ MGI:2176791
cn2
 		Fgf4tm1Mrc/Fgf4tm1.1Mrc
Tg(Rarb-cre)1Mrc/0 		involves: 129S1/Sv * 129X1/SvJ MGI:3713885
cn3
 		Fgf4tm1Mrc/Fgf4tm2Mrc
Tg(Rarb-cre)1Mrc/0 		involves: 129S1/Sv * 129X1/SvJ MGI:2176789


Genotype
MGI:2176791
hm1
Allelic
Composition		 Fgf4tm1Mrc/Fgf4tm1Mrc
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf4tm1Mrc mutation (0 available); any Fgf4 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:3713885
cn2
Allelic
Composition		 Fgf4tm1Mrc/Fgf4tm1.1Mrc
Tg(Rarb-cre)1Mrc/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf4tm1.1Mrc mutation (0 available); any Fgf4 mutation (30 available)
Fgf4tm1Mrc mutation (0 available); any Fgf4 mutation (30 available)
Tg(Rarb-cre)1Mrc mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
limbs/digits/tail phenotype ( J:60091 )
N
• mutants at E15.5, at birth, and as adults have normal forelimbs




Genotype
MGI:2176789
cn3
Allelic
Composition		 Fgf4tm1Mrc/Fgf4tm2Mrc
Tg(Rarb-cre)1Mrc/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf4tm1Mrc mutation (0 available); any Fgf4 mutation (30 available)
Fgf4tm2Mrc mutation (0 available); any Fgf4 mutation (30 available)
Tg(Rarb-cre)1Mrc mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
limbs/digits/tail phenotype ( J:60091 )
N
• no abnormal limbs/digits/tail phenotypes detected

skeleton
skeleton phenotype ( J:60091 )
N
• no abnormal skeleton phenotypes detected




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory