About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pax9+
wild type
MGI:1857888
Summary 6 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Pax9em1(IMPC)Ccpcz/Pax9+ C57BL/6NCrl-Pax9em1(IMPC)Ccpcz/Ph MGI:8298425
ht2
 		Pax9tm1.2(Osr2)Jian/Pax9+ involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6J * FVB/N MGI:5013436
cx3
 		Msx1tm1Rilm/Msx1+
Pax9tm1Rbal/Pax9+ 		involves: 129 * CD-1 MGI:7294560
cx4
 		Msx1tm1Rilm/Msx1tm1Rilm
Pax9tm1Rbal/Pax9+ 		involves: 129 * CD-1 MGI:7294561
cx5
 		Osr2tm1Jian/Osr2tm1Jian
Pax9tm1.2(Osr2)Jian/Pax9+ 		involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6J * FVB/N MGI:5013437
cx6
 		Osr2tm1Jian/Osr2tm1Jian
Pax9tm1.1(Osr2)Jian/Pax9+ 		involves: 129S1/Sv * C57BL/6J * FVB/N MGI:5013438


Genotype
MGI:8298425
ht1
Allelic
Composition		 Pax9em1(IMPC)Ccpcz/Pax9+
Genetic
Background		 C57BL/6NCrl-Pax9em1(IMPC)Ccpcz/Ph
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax9em1(IMPC)Ccpcz mutation (1 available); any Pax9 mutation (22 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
enlarged heart ( J:211773 )
IMPC - CCP-IMG

craniofacial

growth/size/body
enlarged heart ( J:211773 )
IMPC - CCP-IMG
abnormal tooth morphology ( J:211773 )
IMPC - CCP-IMG
abnormal maxilla morphology ( J:211773 )
IMPC - CCP-IMG
abnormal zygomatic bone morphology ( J:211773 )
IMPC - CCP-IMG
enlarged spleen ( J:211773 )
IMPC - CCP-IMG

hematopoietic system
enlarged spleen ( J:211773 )
IMPC - CCP-IMG

immune system
enlarged spleen ( J:211773 )
IMPC - CCP-IMG

skeleton




Genotype
MGI:5013436
ht2
Allelic
Composition		 Pax9tm1.2(Osr2)Jian/Pax9+
Genetic
Background		 involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax9tm1.2(Osr2)Jian mutation (0 available); any Pax9 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
craniofacial phenotype ( J:173121 )
N
• mice exhibit normal tooth development




Genotype
MGI:7294560
cx3
Allelic
Composition		 Msx1tm1Rilm/Msx1+
Pax9tm1Rbal/Pax9+
Genetic
Background		 involves: 129 * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Msx1tm1Rilm mutation (1 available); any Msx1 mutation (21 available)
Pax9tm1Rbal mutation (0 available); any Pax9 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
decreased tooth number ( J:311535 )
• absence of lower teeth

growth/size/body
decreased tooth number ( J:311535 )
• absence of lower teeth

skeleton
decreased tooth number ( J:311535 )
• absence of lower teeth




Genotype
MGI:7294561
cx4
Allelic
Composition		 Msx1tm1Rilm/Msx1tm1Rilm
Pax9tm1Rbal/Pax9+
Genetic
Background		 involves: 129 * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Msx1tm1Rilm mutation (1 available); any Msx1 mutation (21 available)
Pax9tm1Rbal mutation (0 available); any Pax9 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial

digestive/alimentary system

growth/size/body
cleft palate ( J:311535 )




Genotype
MGI:5013437
cx5
Allelic
Composition		 Osr2tm1Jian/Osr2tm1Jian
Pax9tm1.2(Osr2)Jian/Pax9+
Genetic
Background		 involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Osr2tm1Jian mutation (1 available); any Osr2 mutation (20 available)
Pax9tm1.2(Osr2)Jian mutation (0 available); any Pax9 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
craniofacial phenotype ( J:173121 )
N
• mice exhibit a normal number of teeth
cleft secondary palate ( J:173121 )
• in some mice

digestive/alimentary system
cleft secondary palate ( J:173121 )
• in some mice

growth/size/body
cleft secondary palate ( J:173121 )
• in some mice




Genotype
MGI:5013438
cx6
Allelic
Composition		 Osr2tm1Jian/Osr2tm1Jian
Pax9tm1.1(Osr2)Jian/Pax9+
Genetic
Background		 involves: 129S1/Sv * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Osr2tm1Jian mutation (1 available); any Osr2 mutation (20 available)
Pax9tm1.1(Osr2)Jian mutation (0 available); any Pax9 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
abnormal tooth development ( J:173121 )
• mice exhibit supernumerary tooth germs lingual to the maxillary molar compared with wild-type mice
• at E15.5 and E16.5, the oral epithelium lingual to the mandibular first molar tooth germs is thickened compared to in control mice
• however, the number of teeth in the mandible is normal
cleft secondary palate ( J:173121 )
• in all mice

digestive/alimentary system
cleft secondary palate ( J:173121 )
• in all mice

growth/size/body
abnormal tooth development ( J:173121 )
• mice exhibit supernumerary tooth germs lingual to the maxillary molar compared with wild-type mice
• at E15.5 and E16.5, the oral epithelium lingual to the mandibular first molar tooth germs is thickened compared to in control mice
• however, the number of teeth in the mandible is normal
cleft secondary palate ( J:173121 )
• in all mice

skeleton
abnormal tooth development ( J:173121 )
• mice exhibit supernumerary tooth germs lingual to the maxillary molar compared with wild-type mice
• at E15.5 and E16.5, the oral epithelium lingual to the mandibular first molar tooth germs is thickened compared to in control mice
• however, the number of teeth in the mandible is normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/06/2026
MGI 6.29 		The Jackson Laboratory