Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prrx1tm1Jfm mutation
(1 available);
any
Prrx1 mutation
(31 available)
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limbs/digits/tail
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• forelimbs are 12.5% shorter than controls at E18.5; hindlimbs are significantly shortened
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prrx1tm1Jfm mutation
(1 available);
any
Prrx1 mutation
(31 available)
|
|
|
mortality/aging
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• die soon after birth from respiratory distress
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growth/size/body
homeostasis/metabolism
respiratory system
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• contain markedly reduced numbers of von Willebrand factor-positive blood vessels in lung tissue
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• hypoplastic lung tissue
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cardiovascular system
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• contain markedly reduced numbers of von Willebrand factor-positive blood vessels in lung tissue
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prrx1tm1Jfm mutation
(1 available);
any
Prrx1 mutation
(31 available)
Prrx1tm1Tex mutation
(0 available);
any
Prrx1 mutation
(31 available)
|
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mortality/aging
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• phenotype is stated to be a phenocopy of the single Prrx1tm1Tex homozygotes, however no data is presented in J:51596
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craniofacial
skeleton
respiratory system
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prrx1tm1Jfm mutation
(1 available);
any
Prrx1 mutation
(31 available)
Prrx2tm1Mjk mutation
(0 available);
any
Prrx2 mutation
(11 available)
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mortality/aging
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• phenotypes are stated to be identical to double homozygous Prxx1tm1Tex and Prrx2tm1Mjk mutants, however data is not presented in J:51596
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behavior/neurological
craniofacial
hearing/vestibular/ear
homeostasis/metabolism
limbs/digits/tail
respiratory system
skeleton
vision/eye
digestive/alimentary system
growth/size/body