All Phenotypes Ednrb<s-24Pub> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ednrb^s-24Pub
Pu239 citrate alpha ray induced 24Pub
MGI:1857331

Summary

10 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ednrb^s-24Pub/Ednrb^s-24Pub	involves: 101/Rl * C3H/Rl	MGI:3777993
ht2	Ednrb^s-24Pub/Ednrb⁺	involves: 101/Rl * C3H/Rl	MGI:3777992
ht3	Ednrb^s/Ednrb^s-24Pub	involves: 101/Rl * C3H/Rl	MGI:3777994
cx4	Ednrb^s-24Pub/Ednrb⁺ Mycbp2^m274-4Tpo/Mycbp2⁺	involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ	MGI:3849713
cx5	Ednrb^s-24Pub/Ednrb⁺ m174-16Tpo/m174-16Tpo⁺	involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ	MGI:3849715
cx6	Ednrb^s-24Pub/Ednrb⁺ m128-7Tpo/m128-7Tpo⁺	involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ	MGI:3849718
cx7	Ednrb^s-24Pub/Ednrb⁺ m183-15Tpo/m183-15Tpo⁺	involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ	MGI:3849720
cx8	Ednrb^s-24Pub/Ednrb⁺ m251-2Tpo/m251-2Tpo⁺	involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ	MGI:3849722
cx9	Ednrb^s-24Pub/Ednrb⁺ m283-1Tpo/m283-1Tpo⁺	involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ	MGI:3849726
cx10	Ednrb^s-24Pub/Ednrb^s-24Pub m289-5Tpo/m289-5Tpo⁺	involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ	MGI:3849728

Allelic Composition	Ednrb^s-24Pub/Ednrb^s-24Pub
Genetic Background	involves: 101/Rl * C3H/Rl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrb^s-24Pub mutation (0 available); any Ednrb mutation (103 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:16291 , J:100221 )

Allelic Composition	Ednrb^s-24Pub/Ednrb⁺
Genetic Background	involves: 101/Rl * C3H/Rl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrb^s-24Pub mutation (0 available); any Ednrb mutation (103 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body size ( J:100221 )

• described as small and runted

Allelic Composition	Ednrb^s/Ednrb^s-24Pub
Genetic Background	involves: 101/Rl * C3H/Rl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrb^s mutation (19 available); any Ednrb mutation (103 available)
Ednrb^s-24Pub mutation (0 available); any Ednrb mutation (103 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body size ( J:100221 )

• described as small and runted

pigmentation

white spotting ( J:100221 )

integument

white spotting ( J:100221 )

Allelic Composition	Ednrb^s-24Pub/Ednrb⁺ Mycbp2^m274-4Tpo/Mycbp2⁺
Genetic Background	involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrb^s-24Pub mutation (0 available); any Ednrb mutation (103 available)
Mycbp2^m274-4Tpo mutation (0 available); any Mycbp2 mutation (223 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:149893 )

• mice die of respiratory distress at birth

respiratory system

respiratory distress ( J:149893 )

Allelic Composition	Ednrb^s-24Pub/Ednrb⁺ m174-16Tpo/m174-16Tpo⁺
Genetic Background	involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrb^s-24Pub mutation (0 available); any Ednrb mutation (103 available)
m174-16Tpo mutation (0 available); any m174-16Tpo mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:149893 )

• mice die between E16.5 and E18.5

Allelic Composition	Ednrb^s-24Pub/Ednrb⁺ m128-7Tpo/m128-7Tpo⁺
Genetic Background	involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrb^s-24Pub mutation (0 available); any Ednrb mutation (103 available)
m128-7Tpo mutation (0 available); any m128-7Tpo mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Developmental defects of Ednrb^s-24Pub/Ednrb⁺ m128-7Tpo/m128-7Tpo⁺ embryos

mortality/aging

embryonic lethality, complete penetrance ( J:149893 )

• mice die mid-gestation

embryo

abnormal vitelline vasculature morphology ( J:149893 )

• at E10.5, yolk sacs lack mature blood vessels unlike in wild-type mice

abnormal pharyngeal arch morphology ( J:149893 )

• at E10.5

incomplete embryo turning ( J:149893 )

• at E10.5

cardiovascular system

abnormal vitelline vasculature morphology ( J:149893 )

• at E10.5, yolk sacs lack mature blood vessels unlike in wild-type mice

abnormal direction of heart looping ( J:149893 )

• randomized

hemopericardium ( J:149893 )

• at E10.5

enlarged pericardium ( J:149893 )

• at E10.5

craniofacial

abnormal pharyngeal arch morphology ( J:149893 )

• at E10.5

homeostasis/metabolism

hemopericardium ( J:149893 )

• at E10.5

growth/size/body

abnormal head morphology ( J:149893 )

• at E10.5

Allelic Composition	Ednrb^s-24Pub/Ednrb⁺ m183-15Tpo/m183-15Tpo⁺
Genetic Background	involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrb^s-24Pub mutation (0 available); any Ednrb mutation (103 available)
m183-15Tpo mutation (0 available); any m183-15Tpo mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:149893 )

• mice die by E7.5

Allelic Composition	Ednrb^s-24Pub/Ednrb⁺ m251-2Tpo/m251-2Tpo⁺
Genetic Background	involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrb^s-24Pub mutation (0 available); any Ednrb mutation (103 available)
m251-2Tpo mutation (0 available); any m251-2Tpo mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:149893 )

• mice die prior to weaning

Allelic Composition	Ednrb^s-24Pub/Ednrb⁺ m283-1Tpo/m283-1Tpo⁺
Genetic Background	involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrb^s-24Pub mutation (0 available); any Ednrb mutation (103 available)
m283-1Tpo mutation (0 available); any m283-1Tpo mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:149893 )

• mice die prior to weaning

Allelic Composition	Ednrb^s-24Pub/Ednrb^s-24Pub m289-5Tpo/m289-5Tpo⁺
Genetic Background	involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrb^s-24Pub mutation (0 available); any Ednrb mutation (103 available)
m289-5Tpo mutation (0 available); any m289-5Tpo mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:149893 )

• mice die prior to weaning

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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