Analysis Tools
behavior/neurological
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• mice lose more battles in a social dominance task compared with wild-type mice
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• less frequent exploratory sniffing and grooming on a bar-cross apparatus
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• many homozygotes exhibit a mild, transient, trunk tremor on a bar-cross apparatus
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• slower to transverse a narrow challenge bar
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• show decreased locomotor activity on a bar-cross apparatus
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nervous system
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• optic nerve, cervical spinal cord, and ventral roots exhibit frequent loss of periaxonal cytoplasmic collar, periaxonal collar swelling, cytoplasm within myelin, and redundant myelin, however degree of myelination and its compaction are normal
• the cytoplasmic leaflet of the periaxonal membrane is often fused with the inner compact myelin lamellae to form a dense line
• when present, the cytoplasm of the periaxonal collar is usually disorganized
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• confounded by their impaired startle response
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immune system
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• following anti-IgM or LPS stimulation of splenic B cells
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hematopoietic system
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• following anti-IgM or LPS stimulation of splenic B cells
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cellular
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• following anti-IgM or LPS stimulation of splenic B cells
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