Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Asgr2tm1Her mutation
(2 available);
any
Asgr2 mutation
(20 available)
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mortality/aging
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• following infection with S. pneumoniae, mice exhibit decreased survival compared to similarly treated wild-type mice
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immune system
|
• following infection with S. pneumoniae, mice exhibit decreased survival compared to similarly treated wild-type mice
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Asgr2tm1Her mutation
(2 available);
any
Asgr2 mutation
(20 available)
|
|
|
Allelic Composition |
Asgr2tm1Her/Asgr2+
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Genetic Background |
involves: 129S7/SvEvBrd * C57BL/6 |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Asgr2tm1Her mutation
(2 available);
any
Asgr2 mutation
(20 available)
|
|
|
hematopoietic system
N |
• unlike in St3gal4tm1.1Jxm homozygotes, platelet counts are normal
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homeostasis/metabolism