All Phenotypes t<w18> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

t^w18
t, wild 18
MGI:1857112

Summary

5 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	t^w18/t^w18	Not Specified	MGI:5013810
ht2	t^hr4/t^w18	Not Specified	MGI:5465158
cx3	Nme3^tm1Bgh/Nme3⁺ t^w18/t⁺	involves: 129S1/Sv	MGI:5319399
cx4	t^w18/t⁺ Tiam2^tm1Bgh/Tiam2^tm1Bgh	involves: 129S/SvEv * 129S1/Sv	MGI:6360722
cx5	t^w18/t⁺ Tiam2^tm1Bgh/Tiam2⁺ Tg(Ace-Tiam2)C11S1Bgh/0	involves: 129S/SvEv * 129S1/Sv	MGI:6360725

Allelic Composition	t^w18/t^w18
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t^w18 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:23646 )

• between E9 and E10

• embryos are dead or show signs of deterioration and impending death

embryo

abnormal primitive streak formation ( J:23646 )

• at E7 histological analysis reveals a thickening of the egg cylinder in the region of the primitive streak

• at E8 distinctive overgrowth of the primitive streak is seen, with a median bulge projecting dorsally into the amniotic cavity

Allelic Composition	t^hr4/t^w18
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t^hr4 mutation (0 available); any t mutation (19 available)
t^w18 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:169366 )

N	• mice are viable

Allelic Composition	Nme3^tm1Bgh/Nme3⁺ t^w18/t⁺
Genetic Background	involves: 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nme3^tm1Bgh mutation (0 available); any Nme3 mutation (10 available)
t^w18 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:183481 )

• mice exhibit increased transmission of the t-haplotype compared with wild-type mice

Allelic Composition	t^w18/t⁺ Tiam2^tm1Bgh/Tiam2^tm1Bgh
Genetic Background	involves: 129S/SvEv * 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tiam2^tm1Bgh mutation (0 available); any Tiam2 mutation (105 available)
t^w18 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:273736 )

• whether alleles are in cis or trans, mice exhibit reduced transmission of t^w18 compared with wild-type mice

Allelic Composition	t^w18/t⁺ Tiam2^tm1Bgh/Tiam2⁺ Tg(Ace-Tiam2)C11S1Bgh/0
Genetic Background	involves: 129S/SvEv * 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Ace-Tiam2)C11S1Bgh mutation (0 available)
Tiam2^tm1Bgh mutation (0 available); any Tiam2 mutation (105 available)
t^w18 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:273736 )

• mice exhibit increased transmission of t^w18 compared with wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23