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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
stm
stumpy
MGI:1857057
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
stm/stm involves: CBA/FaCam MGI:4839546


Genotype
MGI:4839546
hm1
Allelic
Composition
stm/stm
Genetic
Background
involves: CBA/FaCam
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
stm mutation (1 available); any stm mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• although the mandible is proportionately smaller, the skull itself is not reduced significantly

skeleton
• although the mandible is proportionately smaller, the skull itself is not reduced significantly
• proximal long bones are more severely affected than distal long bones
• shortened but not narrrowed
• the point of muscle attachment at the deltoid tuberosity is increased in size giving the bone a winged shape
• shortened but not narrrowed with poorly developed head
• the point of muscle attachment at the trochanters is increased in size giving the bone a winged shape
• reduction in long bone growth is slightly more severe in proximal than in distal bones (J:5934)
• growth of femora and tibiae is normal until during the first 2 weeks of life then no growth occurs between 16 and 21 days of age after which slow bone growth resumes (J:5934)
• all cartilaginous bone is affected but not all to a degree of significance (J:5970)

growth/size/body
• there is a sudden growth check at 14 days of age
• coincident with failure of newly formed chondrocytes to migrate

limbs/digits/tail
• shortened but not narrrowed
• the point of muscle attachment at the deltoid tuberosity is increased in size giving the bone a winged shape
• shortened but not narrrowed with poorly developed head
• the point of muscle attachment at the trochanters is increased in size giving the bone a winged shape

reproductive system
• Background Sensitivity: evidence suggest modifiers from other backgrounds can increase fertility
• Background Sensitivity: evidence suggest modifiers from other backgrounds can increase fertility





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory