Phenotypes associated with this allele

• Allele Symbol: sb
• Allele Name: stub
• Allele ID: MGI:1857027
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	sb/sb	involves: CF-1	MGI:4821310

Genotype
MGI:4821310

hm1

• Allelic Composition: sb/sb
• Genetic Background: involves: CF-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased survivor rate ( J:245 )

postnatal lethality, incomplete penetrance ( J:245 )

• the majority of mutant mice die by one month of age

skeleton

abnormal skeleton morphology ( J:245 )

• closely resembles Dll3^pu

decreased rib number ( J:245 )

rib fusion ( J:245 )

• irregular fusions are observed

abnormal thoracic cage shape ( J:245 )

• the thoracic basket is wide and flat due to a reduced number of ribs and to fusions of ribs that are present

abnormal vertebral column morphology ( J:245 )

decreased thoracic vertebrae number ( J:245 )

• only 7 could be identified

abnormal spine curvature ( J:245 )

kyphoscoliosis ( J:245 )

lordosis ( J:245 )

abnormal cervical vertebrae morphology ( J:245 )

• numbers 3-5 are asymmetrical, abnormally formed, and fused

abnormal lumbar vertebrae morphology ( J:245 )

• reduced in number, abnormal, and fused

abnormal sacral vertebrae morphology ( J:245 )

• there are elements of four vertebrae, abnormal in shape and arrangement

growth/size/body

decreased body length ( J:245 )

reproductive system

reduced female fertility ( J:245 )

♀

reduced male fertility ( J:245 )

♂

limbs/digits/tail

abnormal tail development ( J:245 )

short tail ( J:245 )

• the tail stub comprises a number of scattered vertebral elements

• there is no bony connection with the rest of the spine