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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Socs2hg
high growth
MGI:1856899
Summary 6 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Socs2hg/Socs2hg involves: AKR/J * C3H/HeJ * C57BL/6J * DBA/2J MGI:2179092
cx2
Mohg1C57BL/6J/Mohg1C57BL/6J
Socs2hg/Socs2hg
involves: C57BL/6J * CAST/EiJ MGI:3608979
cx3
Mohg1C57BL/6J/Mohg1CAST/EiJ
Socs2hg/Socs2hg
involves: C57BL/6J * CAST/EiJ MGI:3608980
cx4
Mohg2C57BL/6J/Mohg2CAST/EiJ
Socs2hg/Socs2hg
involves: C57BL/6J * CAST/EiJ MGI:3608981
cx5
Mohg3C57BL/6J/Mohg3C57BL/6J
Socs2hg/Socs2hg
involves: C57BL/6J * CAST/EiJ MGI:3608983
cx6
Mohg3C57BL/6J/Mohg3CAST/EiJ
Socs2hg/Socs2hg
involves: C57BL/6J * CAST/EiJ MGI:3608985


Genotype
MGI:2179092
hm1
Allelic
Composition
Socs2hg/Socs2hg
Genetic
Background
involves: AKR/J * C3H/HeJ * C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Socs2hg mutation (0 available); any Socs2 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• weaning weight is slightlky lower than expected
• weight gain between 21 and 42 days of age is 30-50% higher in mutant mice compared with wild-type
• weight at maturity remains higher than recorded for wild-type
• weight gain between 21 and 42 days of age is 30-50% higher in mutant mice compared with wild-type

reproductive system
• Background Sensitivity: fertility in both sexes may be normal or as much as 40 per cent lower than recorded for wild-type mice
• Background Sensitivity: 100% of mutant mice are fertile when the genetic background is 96.9% at N5

homeostasis/metabolism
• Background Sensitivity: the maintenance energy requirement in mutant mice is decreased compared with the requirement of wild-type mice
• Background Sensitivity: efficiency of growth of mutant mice is increased compared with wild-type mice




Genotype
MGI:3608979
cx2
Allelic
Composition
Mohg1C57BL/6J/Mohg1C57BL/6J
Socs2hg/Socs2hg
Genetic
Background
involves: C57BL/6J * CAST/EiJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mohg1C57BL/6J mutation (0 available); any Mohg1 mutation (0 available)
Socs2hg mutation (0 available); any Socs2 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• increased growth trajectory




Genotype
MGI:3608980
cx3
Allelic
Composition
Mohg1C57BL/6J/Mohg1CAST/EiJ
Socs2hg/Socs2hg
Genetic
Background
involves: C57BL/6J * CAST/EiJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mohg1C57BL/6J mutation (0 available); any Mohg1 mutation (0 available)
Mohg1CAST/EiJ mutation (0 available); any Mohg1 mutation (0 available)
Socs2hg mutation (0 available); any Socs2 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• increased growth trajectory




Genotype
MGI:3608981
cx4
Allelic
Composition
Mohg2C57BL/6J/Mohg2CAST/EiJ
Socs2hg/Socs2hg
Genetic
Background
involves: C57BL/6J * CAST/EiJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mohg2C57BL/6J mutation (0 available); any Mohg2 mutation (0 available)
Mohg2CAST/EiJ mutation (0 available); any Mohg2 mutation (0 available)
Socs2hg mutation (0 available); any Socs2 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• increased growth trajectory




Genotype
MGI:3608983
cx5
Allelic
Composition
Mohg3C57BL/6J/Mohg3C57BL/6J
Socs2hg/Socs2hg
Genetic
Background
involves: C57BL/6J * CAST/EiJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mohg3C57BL/6J mutation (0 available); any Mohg3 mutation (0 available)
Socs2hg mutation (0 available); any Socs2 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• increased growth trajectory




Genotype
MGI:3608985
cx6
Allelic
Composition
Mohg3C57BL/6J/Mohg3CAST/EiJ
Socs2hg/Socs2hg
Genetic
Background
involves: C57BL/6J * CAST/EiJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mohg3C57BL/6J mutation (0 available); any Mohg3 mutation (0 available)
Mohg3CAST/EiJ mutation (0 available); any Mohg3 mutation (0 available)
Socs2hg mutation (0 available); any Socs2 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• increased growth trajectory





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory