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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		t6
t, 6
MGI:1856562
Summary 14 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		t6/th17 Not Specified MGI:4821281
ht2
 		th20/t6 Not Specified MGI:4868622
ht3
 		t6/thr4 Not Specified MGI:5465156
ht4
 		t6/th57 Not Specified MGI:5465161
ht5
 		thr1/t6 Not Specified MGI:5465172
cx6
 		T30H/T+
t6/t+ 		involves: 101/H * C3H/HeH * TFH MGI:3719859
cx7
 		T32H/T+
t6/t+ 		involves: 101/H * C3H/HeH * TFH MGI:3719860
cx8
 		T36H/T+
t6/t+ 		involves: 101/H * C3H/HeH * TFH MGI:3719862
cx9
 		t6/Tagaptm1Bgh involves: BALB/c * BTBR/TF * FVB/N MGI:3639742
cx10
 		T29H/T+
t6/t+ 		involves: BALB/c * TFH MGI:3719858
cx11
 		T4J/t6 involves: BALB/cBy MGI:4830251
cx12
 		T5J/t6 involves: C57BL/6J MGI:4830536
cx13
 		T/t6 Not Specified MGI:3663265
cx14
 		t6/t+
Tg(Ace-Nme3)H17Bgh/0 		Not Specified MGI:5319402


Genotype
MGI:4821281
ht1
Allelic
Composition		 t6/th17
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t6 mutation (0 available); any t mutation (19 available)
th17 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:4868622
ht2
Allelic
Composition		 th20/t6
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t6 mutation (0 available); any t mutation (19 available)
th20 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:5465156
ht3
Allelic
Composition		 t6/thr4
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t6 mutation (0 available); any t mutation (19 available)
thr4 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:5465161
ht4
Allelic
Composition		 t6/th57
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t6 mutation (0 available); any t mutation (19 available)
th57 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:5465172
ht5
Allelic
Composition		 thr1/t6
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t6 mutation (0 available); any t mutation (19 available)
thr1 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:3719859
cx6
Allelic
Composition		 T30H/T+
t6/t+
Genetic
Background		 involves: 101/H * C3H/HeH * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T30H mutation (0 available); any T mutation (60 available)
t6 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
transmission ratio distortion ( J:62655 )
• the transmission ratio distortion associated with t6 is increased




Genotype
MGI:3719860
cx7
Allelic
Composition		 T32H/T+
t6/t+
Genetic
Background		 involves: 101/H * C3H/HeH * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T32H mutation (0 available); any T mutation (60 available)
t6 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
transmission ratio distortion ( J:62655 )
• the transmission ratio distortion associated with t6 is increased




Genotype
MGI:3719862
cx8
Allelic
Composition		 T36H/T+
t6/t+
Genetic
Background		 involves: 101/H * C3H/HeH * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T36H mutation (0 available); any T mutation (60 available)
t6 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
transmission ratio distortion ( J:62655 )
• the transmission ratio distortion associated with t6 is increased




Genotype
MGI:3639742
cx9
Allelic
Composition		 t6/Tagaptm1Bgh
Genetic
Background		 involves: BALB/c * BTBR/TF * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t6 mutation (0 available); any t mutation (19 available)
Tagaptm1Bgh mutation (0 available); any Tagap mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal sperm motility ( J:100859 )
• compromised sperm motility is inferred as overexpression of Tagap1 results in greater than normal t6 haplotype transmission
abnormal male meiosis ( J:100859 )
• reduced transmission found for sperm bearing t6

cellular
abnormal sperm motility ( J:100859 )
• compromised sperm motility is inferred as overexpression of Tagap1 results in greater than normal t6 haplotype transmission




Genotype
MGI:3719858
cx10
Allelic
Composition		 T29H/T+
t6/t+
Genetic
Background		 involves: BALB/c * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T29H mutation (0 available); any T mutation (60 available)
t6 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
transmission ratio distortion ( J:62655 )
• the transmission ratio distortion associated with t6 is increased




Genotype
MGI:4830251
cx11
Allelic
Composition		 T4J/t6
Genetic
Background		 involves: BALB/cBy
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T4J mutation (1 available); any T mutation (60 available)
t6 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:4830536
cx12
Allelic
Composition		 T5J/t6
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T5J mutation (1 available); any T mutation (60 available)
t6 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:3663265
cx13
Allelic
Composition		 T/t6
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (23 available); any T mutation (60 available)
t6 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
decreased ventral ectodermal ridge size ( J:15081 )
• the size of the ventral ectodermal ridge of the tail (VER) is reduced to 69% of the normal size

embryo
abnormal notochord morphology ( J:15081 )
• the notochord is increased in bulk not only in the distal growth zone (as in T heterozygotes) but in the whole tail, in the cloacal region and even more anteriorly in the lumbar region and has large lumina
• the notochord is present throughout the length of the tail, however it becomes incorporated into the neural tube throughout the tail and often the cloacal region
decreased ventral ectodermal ridge size ( J:15081 )
• the size of the ventral ectodermal ridge of the tail (VER) is reduced to 69% of the normal size




Genotype
MGI:5319402
cx14
Allelic
Composition		 t6/t+
Tg(Ace-Nme3)H17Bgh/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t6 mutation (0 available); any t mutation (19 available)
Tg(Ace-Nme3)H17Bgh mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
transmission ratio distortion ( J:183481 )
• the transmission ratio distortion associated with t6 is decreased




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory