Phenotypes associated with this allele
Allelic Composition |
Oca2p/Oca2p
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|
Genetic Background |
Not Specified |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
|
|
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-61H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-96H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
craniofacial
digestive/alimentary system
growth/size/body
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-88H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
integument
|
• similar to homozygous Oca2p mice
(J:2108)
• on this background reduced pigmentation in the coat results in a yellow coat color
(J:78801)
|
pigmentation
|
• similar to homozygous Oca2p mice
(J:2108)
• on this background reduced pigmentation in the coat results in a yellow coat color
(J:78801)
|
|
• eye color has a pink tint, similar to the eyes of albino mice
|
vision/eye
|
• eye color has a pink tint, similar to the eyes of albino mice
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-93H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-92H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-66H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
integument
|
• ruby eyes, light colored ears and tail, sandy brown tips to fur, dark under fur
|
pigmentation
|
• ruby eyes, light colored ears and tail, sandy brown tips to fur, dark under fur
|
limbs/digits/tail
vision/eye
Allelic Composition |
Oca2p-95H/Oca2p
|
|
Genetic Background |
involves: 101/H * C3H/HeH |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-95H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
Allelic Composition |
Oca2p-98H/Oca2p
|
|
Genetic Background |
involves: 101/H * C3H/HeH |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-98H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
Allelic Composition |
Oca2p-86H/Oca2p
|
|
Genetic Background |
involves: 101/H * C3H/HeH |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-86H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
integument
|
• color is similar to homozygous Oca2p mice
(J:2108)
• on this background reduced pigmentation in the coat results in a yellow coat color
(J:78801)
|
pigmentation
|
• color is similar to homozygous Oca2p mice
(J:2108)
• on this background reduced pigmentation in the coat results in a yellow coat color
(J:78801)
|
|
• eyes have a pink tint, resembling eyes of albino mice
|
vision/eye
|
• eyes have a pink tint, resembling eyes of albino mice
|
Allelic Composition |
Oca2p-87H/Oca2p
|
|
Genetic Background |
involves: 101/H * C3H/HeH |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-87H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
integument
|
• color is similar to homozygous Oca2p mice
(J:2108)
• on this background reduced pigmentation in the coat results in a yellow coat color
(J:78801)
|
pigmentation
|
• color is similar to homozygous Oca2p mice
(J:2108)
• on this background reduced pigmentation in the coat results in a yellow coat color
(J:78801)
|
|
• eye color has a pink tint, similar to the eyes of albino mice
|
vision/eye
|
• eye color has a pink tint, similar to the eyes of albino mice
|
Allelic Composition |
Oca2p-55H/Oca2p
|
|
Genetic Background |
involves: 101/H * C3H/HeH |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-55H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
Allelic Composition |
Oca2p-91H/Oca2p
|
|
Genetic Background |
involves: 101/H * C3H/HeH |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-91H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
Allelic Composition |
Oca2p/Oca2p-80K
|
|
Genetic Background |
involves: 101/Rl * C3H/Rl |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-80K mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
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pigmentation
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• reduced eumelanin pigmentation in hair
|
vision/eye
integument
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• reduced eumelanin pigmentation in hair
|
Allelic Composition |
Oca2p/Oca2p-7R
|
|
Genetic Background |
involves: 101/Rl * C3H/Rl |
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pigmentation
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• reduced eumelanin in the hair
• pigmentation intermediate between Oca2p/Oca2p and wild-type
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vision/eye
integument
|
• reduced eumelanin in the hair
• pigmentation intermediate between Oca2p/Oca2p and wild-type
|
pigmentation
|
• reduced eumelanin pigmentation in hair
|
vision/eye
integument
|
• reduced eumelanin pigmentation in hair
|
Allelic Composition |
Oca2p/Oca2p-116G
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|
Genetic Background |
involves: 101/Rl * C3H/Rl |
|
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pigmentation
|
• reduced eumelanin pigmentation in hair
|
vision/eye
integument
|
• reduced eumelanin pigmentation in hair
|
Allelic Composition |
Oca2p/Oca2p-103G
|
|
Genetic Background |
involves: 101/Rl * C3H/Rl |
|
|
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pigmentation
|
• reduced eumelanin pigmentation in hair
• fur darker than Oca2p/Oca2p
|
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• eye pigment reduced, but eyes virtually fully pigmented from birth on
|
vision/eye
|
• eye pigment reduced, but eyes virtually fully pigmented from birth on
|
integument
|
• reduced eumelanin pigmentation in hair
• fur darker than Oca2p/Oca2p
|
Allelic Composition |
Oca2p-85H/Oca2p
|
|
Genetic Background |
involves: C3H/HeH |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-85H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
integument
|
• mice resemble Oca2p homozygotes
|
pigmentation
|
• mice resemble Oca2p homozygotes
|
Allelic Composition |
Oca2p-65H/Oca2p
|
|
Genetic Background |
involves: C3H/HeH |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-65H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
pigmentation
|
• eye color is darker tha in Oca2p homozygotes
|
vision/eye
|
• eye color is darker tha in Oca2p homozygotes
|
Allelic Composition |
Oca2p-78H/Oca2p
|
|
Genetic Background |
involves: C3H/HeH |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-78H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
Allelic Composition |
Oca2p-80H/Oca2p
|
|
Genetic Background |
involves: C3H/HeH |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-80H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
integument
|
• mice resemble Oca2p homozygotes
|
pigmentation
|
• mice resemble Oca2p homozygotes
|
Allelic Composition |
Oca2p-83H/Oca2p
|
|
Genetic Background |
involves: C3H/HeH |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Oca2p-83H mutation
(0 available);
any
Oca2 mutation
(69 available)
|
|
|
integument
|
• coat is slightly darker than in Oca2p homozygotes
|
pigmentation
|
• coat is slightly darker than in Oca2p homozygotes
|
pigmentation
|
• coat color (eumelanin pigment) is intermediate between the coat color of Oca2p/Oca2p and wild-type mice
|
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• eyes of newborns are not fully pigmented and darken with age
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vision/eye
|
• eyes of newborns are not fully pigmented and darken with age
|
integument
|
• coat color (eumelanin pigment) is intermediate between the coat color of Oca2p/Oca2p and wild-type mice
|
pigmentation
|
• dark sepia in color
• unlike mice wildtype for pink-eye the hairs are pigmented from tip to base and do not have large clumps of pigment, but may have small clumps of pigment
|
integument
|
• dark sepia in color
• unlike mice wildtype for pink-eye the hairs are pigmented from tip to base and do not have large clumps of pigment, but may have small clumps of pigment
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lystbg-slt mutation
(0 available);
any
Lyst mutation
(225 available)
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
|
|
|
pigmentation
|
• coat was slightly lighter than those of mice homozygous for p alone
• cortical pigment was absent
• the few medullary septae that lacked pigment were in the distal hair shaf
• granules resembled those of mice homozygous for p alone except a few were larger
|
vision/eye
integument
|
• coat was slightly lighter than those of mice homozygous for p alone
• cortical pigment was absent
• the few medullary septae that lacked pigment were in the distal hair shaf
• granules resembled those of mice homozygous for p alone except a few were larger
|
pigmentation
integument
|
• random thinning of the coat appeared during the third week of age
|
|
• coat thinning at three weeks of age was followed by a short lag in the second hair growth cycle
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2p mutation
(11 available);
any
Oca2 mutation
(69 available)
Tyrc-i mutation
(0 available);
any
Tyr mutation
(376 available)
|
|
|
Allelic Composition |
a/a Oca2p/Oca2p
|
|
Genetic Background |
Not Specified |
|
|
|
limbs/digits/tail
|
• the tail has much less pigment than normal mice
|
pigmentation
|
• the ears appear much lighter than ears of normal mice
(J:78801)
|
|
• black and brown pigmentation in hair is significantly reduced
|
|
• pigment granules are not diluted but no longer evenly distributed, found as flecks and large loose clumps
• the color quality of the pigment is not altered but there are fewer cortical granules and an increase in pigmentation lag
|
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• pigment occurs in loose clumps
|
|
• the tail has much less pigment than normal mice
|
|
• eyes are similar in color to eyes of albino mice
|
vision/eye
|
• eyes are similar in color to eyes of albino mice
|
craniofacial
|
• the ears appear much lighter than ears of normal mice
(J:78801)
|
hearing/vestibular/ear
|
• the ears appear much lighter than ears of normal mice
(J:78801)
|
integument
|
• the ears appear much lighter than ears of normal mice
(J:78801)
|
|
• black and brown pigmentation in hair is significantly reduced
|
|
• pigment granules are not diluted but no longer evenly distributed, found as flecks and large loose clumps
• the color quality of the pigment is not altered but there are fewer cortical granules and an increase in pigmentation lag
|
|
• pigment occurs in loose clumps
|
|
• the tail has much less pigment than normal mice
|
growth/size/body
|
• the ears appear much lighter than ears of normal mice
(J:78801)
|