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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tyrc-a
acromelanic
MGI:1855983
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Tyrc-a/Tyrc-a C3H/HeJ-Tyrc-a/J MGI:3766257
ht2
Tyrc/Tyrc-a involves: C3H/HeJ MGI:4360390
ht3
Tyrc-a/Tyrc-ch involves: C3H/HeJ MGI:4360397
ht4
Tyrc-a/Tyrc-e involves: C3H/HeJ MGI:4360477
ht5
Tyrc-a/Tyrc-h involves: C3H/HeJ MGI:4360479


Genotype
MGI:3766257
hm1
Allelic
Composition
Tyrc-a/Tyrc-a
Genetic
Background
C3H/HeJ-Tyrc-a/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc-a mutation (2 available); any Tyr mutation (375 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
N
• no aberrant bleeding time after tail vein nick

integument
• young and adult have an off-white coat color and eyes, ears, tail and anal regions are pigmented
• in the albino series, coat appearance is between chinchilla and extreme dilution

pigmentation
• young and adult have an off-white coat color and eyes, ears, tail and anal regions are pigmented
• in the albino series, coat appearance is between chinchilla and extreme dilution




Genotype
MGI:4360390
ht2
Allelic
Composition
Tyrc/Tyrc-a
Genetic
Background
involves: C3H/HeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc mutation (79 available); any Tyr mutation (375 available)
Tyrc-a mutation (2 available); any Tyr mutation (375 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• slightly off-white coat color
• ear and tail hairs are slightly sooty
• eyes are dark but no comparison to wild-type given

vision/eye
• eyes are dark but no comparison to wild-type given

integument
• slightly off-white coat color
• ear and tail hairs are slightly sooty




Genotype
MGI:4360397
ht3
Allelic
Composition
Tyrc-a/Tyrc-ch
Genetic
Background
involves: C3H/HeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc-a mutation (2 available); any Tyr mutation (375 available)
Tyrc-ch mutation (79 available); any Tyr mutation (375 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• coat color is intermediate between chinchilla and acromelanic homozygotes with a very darkly pigmented anal region

integument
• coat color is intermediate between chinchilla and acromelanic homozygotes with a very darkly pigmented anal region




Genotype
MGI:4360477
ht4
Allelic
Composition
Tyrc-a/Tyrc-e
Genetic
Background
involves: C3H/HeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc-a mutation (2 available); any Tyr mutation (375 available)
Tyrc-e mutation (4 available); any Tyr mutation (375 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• this heterozygous compound has a lighter coat but darker ears and tail hair than Tyrc-e homozygotes
• appearance is indistinguishable from Tyrc-a homozygotes

integument
• this heterozygous compound has a lighter coat but darker ears and tail hair than Tyrc-e homozygotes
• appearance is indistinguishable from Tyrc-a homozygotes




Genotype
MGI:4360479
ht5
Allelic
Composition
Tyrc-a/Tyrc-h
Genetic
Background
involves: C3H/HeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc-a mutation (2 available); any Tyr mutation (375 available)
Tyrc-h mutation (2 available); any Tyr mutation (375 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• the coat is lighter than mice that are homozygous Tyrc-h but indistinguishable from acromelanic homozygotes

integument
• the coat is lighter than mice that are homozygous Tyrc-h but indistinguishable from acromelanic homozygotes





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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory