Phenotypes associated with this allele

• Allele Symbol: Tyr^c-p
• Allele Name: platinum
• Allele ID: MGI:1855981
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tyr^c-p/Tyr^c-p	involves: AKR/J * DBA/2J	MGI:3833939
hm2	Tyr^c-p/Tyr^c-p	involves: C57BL/6	MGI:3794762
ht3	Tyr^c-p/Tyr^c	Not Specified	MGI:4366464

Genotype
MGI:3833939

hm1

• Allelic Composition: Tyr^c-p/Tyr^c-p
• Genetic Background: involves: AKR/J * DBA/2J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:13442 )

• mice are a shade darker than albino

absent eye pigmentation ( J:13442 )

• eyes appear pink

hypopigmentation ( J:13442 )

vision/eye

absent eye pigmentation ( J:13442 )

• eyes appear pink

integument

abnormal coat/hair pigmentation ( J:13442 )

• mice are a shade darker than albino

shiny fur ( J:13442 )

• the coat has a lustre or sheen

Genotype
MGI:3794762

hm2

• Allelic Composition: Tyr^c-p/Tyr^c-p
• Genetic Background: involves: C57BL/6

pigmentation

abnormal hair follicle melanogenesis ( J:6611 , J:13319 )

• the amount of melanin found in anagen hairbulbs is reduced by more than 20-fold compared to wild-type mice (J:6611)

• affected mice fail to produce a tyrsoinase isoform with a carboxy-terminal PEP7 epitope, which participates in a high molecular weight complex important to melanogenesis (J:13319)

diluted coat color ( J:6611 )

• mice have slight pigmentation of the coat

integument

abnormal hair follicle melanogenesis ( J:6611 , J:13319 )

• the amount of melanin found in anagen hairbulbs is reduced by more than 20-fold compared to wild-type mice (J:6611)

• affected mice fail to produce a tyrsoinase isoform with a carboxy-terminal PEP7 epitope, which participates in a high molecular weight complex important to melanogenesis (J:13319)

diluted coat color ( J:6611 )

• mice have slight pigmentation of the coat

Genotype
MGI:4366464

ht3

• Allelic Composition: Tyr^c-p/Tyr^c
• Genetic Background: Not Specified

pigmentation

abnormal coat/hair pigmentation ( J:13442 )

• the coat is intermediate between the homozygote and albino

integument

abnormal coat/hair pigmentation ( J:13442 )

• the coat is intermediate between the homozygote and albino