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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		As
agouti suppressor
MGI:1855934
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		As/As
A/A 		involves: 101/H * C3H/HeH MGI:4418456
cx2
 		Aw/Aw
As/As 		involves: 101/H * C3H/HeH MGI:4418714
cx3
 		at/A
As/As+ 		Not Specified MGI:4418457
cx4
 		at/at
As/As 		Not Specified MGI:4418719
cx5
 		Aw/at
As/As+ 		Not Specified MGI:4418722


Genotype
MGI:4418456
cx1
Allelic
Composition		 As/As
A/A
Genetic
Background		 involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A mutation (19 available); any a mutation (463 available)
As mutation (0 available); any As mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
darkened coat color ( J:5027 )
• amount of yellow pigment produced by an agouti genotype is reduced and coat is darker than expected
• the normally yellow pinna hairs for all agouti alleles except ae are black (or brown on a homozygous brown background)

integument
darkened coat color ( J:5027 )
• amount of yellow pigment produced by an agouti genotype is reduced and coat is darker than expected
• the normally yellow pinna hairs for all agouti alleles except ae are black (or brown on a homozygous brown background)




Genotype
MGI:4418714
cx2
Allelic
Composition		 Aw/Aw
As/As
Genetic
Background		 involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
As mutation (0 available); any As mutation (0 available)
Aw mutation (14 available); any a mutation (463 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
darkened coat color ( J:5027 )
• the size of the yellow band and percentage of banded hairs are reduced darkening the over-all coat
• the top of the head is nearly non-agouti
• the belly is dark agouti rather than the expected white or cream color

integument
darkened coat color ( J:5027 )
• the size of the yellow band and percentage of banded hairs are reduced darkening the over-all coat
• the top of the head is nearly non-agouti
• the belly is dark agouti rather than the expected white or cream color




Genotype
MGI:4418457
cx3
Allelic
Composition		 at/A
As/As+
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A mutation (19 available); any a mutation (463 available)
As mutation (0 available); any As mutation (0 available)
at mutation (8 available); any a mutation (463 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
abnormal coat/hair pigmentation ( J:5027 )
• only the agouti allele on the same chromosome as the As allele is affected
• the expected cream belly is not seen for this genotype; the mouse looks normal agouti

integument
abnormal coat/hair pigmentation ( J:5027 )
• only the agouti allele on the same chromosome as the As allele is affected
• the expected cream belly is not seen for this genotype; the mouse looks normal agouti




Genotype
MGI:4418719
cx4
Allelic
Composition		 at/at
As/As
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
As mutation (0 available); any As mutation (0 available)
at mutation (8 available); any a mutation (463 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
abnormal coat/hair pigmentation ( J:5027 )
• unable to distinguish from homozygous ae mice
darkened coat color ( J:5027 )
• the entire coat is dark-agouti; a cream belly is normally found on mice that are homozygous for at

integument
abnormal coat/hair pigmentation ( J:5027 )
• unable to distinguish from homozygous ae mice
darkened coat color ( J:5027 )
• the entire coat is dark-agouti; a cream belly is normally found on mice that are homozygous for at




Genotype
MGI:4418722
cx5
Allelic
Composition		 Aw/at
As/As+
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
As mutation (0 available); any As mutation (0 available)
at mutation (8 available); any a mutation (463 available)
Aw mutation (14 available); any a mutation (463 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
abnormal coat/hair pigmentation ( J:5027 )
• this allele only affects the agouti allele present on the same chromosome
• this genotype results in normal light-bellied agouti; not the anticipated cream color from the at allele and seen in a mouse genotype AsAw/As<+>at

integument
abnormal coat/hair pigmentation ( J:5027 )
• this allele only affects the agouti allele present on the same chromosome
• this genotype results in normal light-bellied agouti; not the anticipated cream color from the at allele and seen in a mouse genotype AsAw/As<+>at




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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory