As
Radiation induced Allele Detail

Summary

• Symbol: As
• Name: agouti suppressor
• MGI ID: MGI:1855934
• Synonyms: A^s, As, In(1)2H
• Gene: As Location: unknown Genetic Position: Chr2, Syntenic
• Alliance: As page

Mutation origin

• Strain of Origin: (C3H/HeH x 101/H)F1

Mutation description

• Allele Type: Radiation induced
• Mutation: Inversion
• As involves 1 genes/genome features (As) View all
• Mutation details: As is associated with a long inversion, In(1)2H, which suppresses crossing over between Pldn and As and increases crossing-over between a and Gdf5. (J:13742)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any As Mutation: 0 strains or lines available

Notes

The effect in heterozygotes with other agouti-locus alleles (A^s A^w/+ x, where x = A^w, A, a^t, or a) is more pronounced in the pinna, tail, and hindfoot than in the body pelage (J:12033).

References

• Original: J:5027 Phillips RJS, A cis-trans position effect at the A locus of the house mouse. Genetics. 1966 Aug;54(2):485-95
• All: 6 reference(s)