Rpap2^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rpap2^em1Gpt
• Name: RNA polymerase II associated protein 2; endonuclease-mediated mutation 1, GemPharmatech
• MGI ID: MGI:8474992
• Gene: Rpap2 Location: Chr5:107745239-107809704 bp, + strand Genetic Position: Chr5, 52.23 cM
• Alliance: Rpap2^em1Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR/Cas-mediated targeting floxed exons 4 through 6. (J:364423)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rpap2 Mutation: 38 strains or lines available

References

• Original: J:364423 Cui D, et al., The FBXW7-RPAP2 Axis Controls the Growth of Hepatocellular Carcinoma Cells and Determines the Fate of Liver Cell Differentiation. Adv Sci (Weinh). 2025 Apr;12(13):e2404718
• All: 1 reference(s)