Tsr3^em1Iad
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tsr3^em1Iad
• Name: TSR3 20S rRNA accumulation; endonuclease-mediated mutation 1, Igor Adameyko
• MGI ID: MGI:8399308
• Synonyms: Tsr3^-
• Gene: Tsr3 Location: Chr17:25459141-25461773 bp, + strand Genetic Position: Chr17, 12.53 cM
• Alliance: Tsr3^em1Iad page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details:

  CRISPR/Cas-mediated targeting deleted 1783 bp of the sequence encompassing exon 2 through 5 to generate a null allele, as confirmed by Sanger sequencing. (J:381064)

Expression

In Mice Carrying this Mutation:	13 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tsr3 Mutation: 14 strains or lines available

References

• Original: J:381064 Poverennaya I, et al., Ribosomal modifications are associated with mesenchymal fate selection in the neural crest lineage. Nat Commun. 2026 Mar 9;17(1)
• All: 1 reference(s)