4930447C04Rik^em2Qsh
Endonuclease-mediated Allele Detail

Summary

• Symbol: 4930447C04Rik^em2Qsh
• Name: RIKEN cDNA 4930447C04 gene; endonuclease-mediated mutation 2, Qinghua Shi
• MGI ID: MGI:8323063
• Synonyms: Six6os1^-
• Gene: 4930447C04Rik Location: Chr12:72926967-72964742 bp, - strand Genetic Position: Chr12, 30.3 cM, cytoband C3
• Alliance: 4930447C04Rik^em2Qsh page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details:

  CRISPR-targeting of exon 4 deleted 5 bp from the coding region (GRCm39:12:72962183-72962187delCTCAT), leading to a frameshift and premature stop codon (c.176_180del p.Asp59Glyfs*7). (J:383089)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any 4930447C04Rik Mutation: 29 strains or lines available

References

• Original: J:383089 Fan S, et al., A novel recombination protein C12ORF40/REDIC1 is required for meiotic crossover formation. Cell Discov. 2023 Aug 23;9(1):88
• All: 1 reference(s)