Gpr158^tm1.1Jdw
Targeted Allele Detail

Summary

• Symbol: Gpr158^tm1.1Jdw
• Name: G protein-coupled receptor 158; targeted mutation 1.1, Joris de Wit
• MGI ID: MGI:8318985
• Synonyms: Gpr158^f, Gpr158^flox
• Gene: Gpr158 Location: Chr2:21372378-21835355 bp, + strand Genetic Position: Chr2, 14.92 cM
• Alliance: Gpr158^tm1.1Jdw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:372545
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 4 was flanked by loxP sites and a neomycin resistance cassette flanked by rox sites was inserted. The neomycin selection cassette was removed in the ES cells. (J:372545)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr158 Mutation: 77 strains or lines available

References

• Original: J:372545 Verpoort B, et al., A postsynaptic GPR158-PLCXD2 complex controls spine apparatus abundance and dendritic spine maturation. Dev Cell. 2025 Sep 22;60(18):2470-2486.e10
• All: 1 reference(s)