Efcab5^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Efcab5^em1Osb
• Name: EF-hand calcium binding domain 5; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:8280444
• Gene: Efcab5 Location: Chr11:76980741-77079794 bp, - strand Genetic Position: Chr11, 46.25 cM
• Alliance: Efcab5^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NCrSlc x DBA/2CrSlc)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a large deletion which includes exons 5-13. (J:377938)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Efcab5 Mutation: 55 strains or lines available

References

• Original: J:377938 Wang H, et al., Proximity labeling of axonemal protein CFAP91 identifies EFCAB5 that regulates sperm motility. Nat Commun. 2025 Sep 10;16(1):8238
• All: 1 reference(s)