Smim26^em1Lenh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Smim26^em1Lenh
• Name: small integral membrane protein 26; endonuclease-mediated mutation 1, Lena Ho
• MGI ID: MGI:8278444
• Gene: Smim26 Location: Chr2:144435985-144437286 bp, + strand Genetic Position: Chr2, 71.02 cM
• Alliance: Smim26^em1Lenh page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exon 1. (J:375177)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smim26 Mutation: 5 strains or lines available

References

• Original: J:375177 Nah J, et al., Microprotein SMIM26 drives oxidative metabolism via serine-responsive mitochondrial translation. Mol Cell. 2025 Jul 17;85(14):2759-2775.e12
• All: 1 reference(s)