Rprm^em2Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rprm^em2Gpt
• Name: reprimo, TP53 dependent G2 arrest mediator candidate; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
• MGI ID: MGI:8260983
• Gene: Rprm Location: Chr2:53974105-53975564 bp, - strand Genetic Position: Chr2, 30.69 cM, cytoband C1
• Alliance: Rprm^em2Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed the single coding exon. (J:370306)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rprm Mutation: 8 strains or lines available

References

• Original: J:370306 Zhang Y, et al., RPRM negatively regulates ATM levels through its nuclear translocation on irradiation mediated by CDK4/6 and IPO11. iScience. 2022 Oct 21;25(10):105115
• All: 1 reference(s)