Ufsp1^em1Dpmi
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ufsp1^em1Dpmi
• Name: UFM1-specific peptidase 1; endonuclease-mediated mutation 1, Douglas P Millay
• MGI ID: MGI:8255238
• Gene: Ufsp1 Location: Chr5:137292931-137293926 bp, + strand Genetic Position: Chr5, 76.33 cM
• Alliance: Ufsp1^em1Dpmi page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology deleted approximately 466 bp. RT-qPCR analysis across multiple tissues confirmed the absence of expression. (J:372394)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ufsp1 Mutation: 5 strains or lines available

References

• Original: J:372394 Calvo C, et al., Loss of Ufsp1 does not cause major changes at the neuromuscular junction. PLoS One. 2025;20(8):e0328690
• All: 1 reference(s)