Krt19^{em1(cre/ERT2)Bji}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Krt19^{em1(cre/ERT2)Bji}
• Name: keratin 19; Baoan Ji
• MGI ID: MGI:8248662
• Synonyms: CK19-CreER
• Gene: Krt19 Location: Chr11:100031636-100036752 bp, - strand Genetic Position: Chr11, 63.42 cM
• Alliance: Krt19^{em1(cre/ERT2)Bji} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Krt19^{em1(cre/ERT2)Bji} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Krt19 (MGI:96693)

• Mutation details: CRISPR/Cas9 genome editing technology was used to insert an IRES-CreERT2 cassette into the mouse Krt19 gene between the translation stop and 3' UTR. (J:372355)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Krt19 (mouse) Summary of all recombinase alleles driven by Krt19. Alliance mouse Krt19 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Krt19 Mutation: 21 strains or lines available

References

• Original: J:372355 Wang B, et al., A novel mouse model of diverse tumors derived from epithelial cells. Physiol Rep. 2025 Apr;13(7):e70289
• All: 1 reference(s)