Snx4^tm1.1Vwj
Targeted Allele Detail

Summary

• Symbol: Snx4^tm1.1Vwj
• Name: sorting nexin 4; targeted mutation 1.1, Jan RT van Weering
• MGI ID: MGI:8246795
• Synonyms: Snx4^lox
• Gene: Snx4 Location: Chr16:33071826-33119932 bp, + strand Genetic Position: Chr16, 23.77 cM
• Alliance: Snx4^tm1.1Vwj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:364837
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted around exons 3 and 4 and a self-excising neo cassette was inserted via homologous recombination. The neo cassette was then removed. (J:364837)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Snx4 Mutation: 27 strains or lines available

References

• Original: J:364837 Poppinga J, et al., Endosomal sorting protein SNX4 limits synaptic vesicle docking and release. Elife. 2024 Dec 19;13
• All: 1 reference(s)