Zfp488^tm1Qrlu
Targeted Allele Detail

Summary

• Symbol: Zfp488^tm1Qrlu
• Name: zinc finger protein 488; targeted mutation 1, Q Richard Lu
• MGI ID: MGI:8242623
• Synonyms: Zfp488^KI
• Gene: Zfp488 Location: Chr14:33689027-33700721 bp, - strand Genetic Position: Chr14, 20.8 cM
• Alliance: Zfp488^tm1Qrlu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:371392
• Parent Cell Line: SM1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding region was replaced with an H2b-GFP/neo cassette. The cassette is fused in-frame immediately after the translation start. GFP expression is seen in oligodendrocyte lineage cells. (J:371392)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp488 Mutation: 10 strains or lines available

References

• Original: J:371392 Cui S, et al., Zinc-Finger Protein ZFP488 Regulates the Timing of Oligodendrocyte Myelination and Remyelination. J Neurosci. 2024 Sep 25;44(39)
• All: 1 reference(s)