Ccer1^em1Zbhu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ccer1^em1Zbhu
• Name: coiled-coil glutamate-rich protein 1; endonuclease-mediated mutation 1, Zhibin Hu
• MGI ID: MGI:8237793
• Synonyms: Ccer1^-8bp
• Gene: Ccer1 Location: Chr10:97528921-97530785 bp, + strand Genetic Position: Chr10, 50.38 cM
• Alliance: Ccer1^em1Zbhu page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of the coding region deleted 8bp and produced a premature stop codon. (J:344358)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccer1 Mutation: 8 strains or lines available

References

• Original: J:344358 Qin D, et al., Phase-separated CCER1 coordinates the histone-to-protamine transition and male fertility. Nat Commun. 2023 Dec 11;14(1):8209
• All: 1 reference(s)